ferecave.blogg.se

1. #RADAR 10 HOMEOPATHIC GRAPHICAL REPRESENTATION HOW TO#
2. #RADAR 10 HOMEOPATHIC GRAPHICAL REPRESENTATION TRIAL#

#RADAR 10 HOMEOPATHIC GRAPHICAL REPRESENTATION TRIAL#

Despite all the positive research and trial about its effectiveness for modifying cholesterol, patients show poor compliance due to muscle problems. These are the most widely prescribed by physician, and average dosage of prescribing are increasing day by day. The first statin to be approved was lovastatin in 1987. It is hypothesized that the inhibition of HMG-CoA reductase by statin decreases intracellular cholesterol biosynthesis in liver thus causing reduction in blood LDL-C which results in decrease of atherogenesis. A major turning point in the evolution of lipid hypothesis occurred in 1976 by a Japan biochemist isolated a factor known as statin from the fungus Penicillium citrinum that is identified as competitive inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA). A great advance was made in 1973 with the discovery of the LDL receptor by Brown and Goldstein, who further identified deficiency of LDL receptors in patients with familial hypercholesterolemia.

Subsequently, LDL-C levels were positively correlated with CVD risk, whereas HDL-C levels were inversely correlated. The term “Dyslipidemia” was introduced in 2006, denoting derangements of one or more of the lipoproteins in blood, such as total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and/or triglycerides (TG), or low levels of high-density lipoprotein cholesterol (HDL-C) alone. Further, it was referred as hyperlipoproteinemia which means condition with abnormally elevated levels of lipoproteins in the blood. In 1980s, hyperlipidemia term was included in medical subject headings which refers to conditions with excess lipids in the blood. Its prevalence is increasing in many developing countries due to westernization of diet, obesity, aging, reduced physical activity, and other adverse lifestyle changes. The four main identified NCDs, by the World Health Organization, are cardiovascular diseases (CVDs) (such as heart attacks and stroke), cancer, chronic respiratory disease (such as chronic obstructed pulmonary disease and asthma), and diabetes mellitus (diabetes).ĭyslipidemia is a modifiable risk factor of CVD, manifested by alteration of lipoproteins and a major cause of morbidity and mortality worldwide. World Health Organization's Country Profiles (2014) for India estimates 60% of the deaths annually due to NCDs. Globally, 38 million people die each year from NCDs. Noncommunicable diseases (NCDs) are chronic diseases with slow progression and continued to evolve slowly with morbidity until it is intervened. Homoeopathy in the management of Dyslipidemia: A short review.

#RADAR 10 HOMEOPATHIC GRAPHICAL REPRESENTATION HOW TO#

How to cite this URL: Bhalerao RD, Manchanda RK, Roja V. How to cite this article: Bhalerao RD, Manchanda RK, Roja V. Keywords: Arteriosclerosis, Atherosclerosis, Cholesterol, Dyslipidemia, Homoeopathy, Lipid However, more well-designed studies are warranted to generate effectiveness/efficacy of Homoeopathy. There are positive leads in managing patients suffering from dyslipidemia. From literary search, medicines commonly used in Materia Medica and drugs of Indian origin were noted. Four preclinical, three observational studies, and two case records were identified. Relevant research was categorized by study type and appraised according to study type and design. A comprehensive search from major biomedical databases including National Medical Library (PubMed), AYUSH PORTAL, EMBASE, and the Cochrane Library was conducted using the search term “dyslipidemia,” “atherosclerosis,” “arteriosclerosis,” “atheroma” along with “Homoeopathy.” In addition, efforts were made to search authoritative texts of authors, such homoeopathic Materia Medica, repertory, etc. Preclinical and clinical studies (case records to controlled trials) are included. No rigid inclusion has been kept due to scarcity of evidence-based literature.

This study reviews the existing information available in Homoeopathy (research and traditional knowledge) for managing dyslipidemia. Statin is the first-line of treatment for dyslipidemia and there are known side effects of statin therapy. The importance of high serum total cholesterol and high level of low-density lipoprotein cholesterol, as a risk factor for coronary artery diseases is well established.